DEMENTIA: TYPES, CAUSES, SYMPTOMS AND TREATMENT

Dementia is not a specific disease. Rather, several diseases cause dementia. The term ‘dementia’ is an umbrella term used to describe symptoms of cognitive impairment, and within the dementia umbrella, there are many different variations.

Dementia is a group of thinking and social symptoms that interferes with daily functioning. Dementia is a group of conditions characterised by impairment of at least two brain functions, such as memory loss and judgement. In Nigeria, there are more than 100,00 cases of dementia per year.

Types of Dementia

There are over 100 types of dementia being researched and treated today. There is dementia resulting from years of alcohol misuse. There is dementia associated with Parkinson’s Disease. There is dementia that is a result of a traumatic brain injury. Of this variety, there are four types of dementia found and treated most commonly. These four are briefly explained below:

1. Alzheimer’s Disease: Alzheimer’s disease is the most common type of dementia. It is characterized by a gradual decline in memory, thinking, behaviour and social skills. Alzheimer’s causes brain cells to shrink and eventually die and is the result of an abnormal build-up of protein around brain cells.

2. Dementia with Lewy Body: People with Lewy Body experience fluctuating cognition; they have moments or periods of clarity and make complete sense followed by other times of confusion and nonsensical thinking. Lewy Body Dementia causes its victims to be extremely sensitive to anti-psychotic medications which can typically help those with either Parkinson’s or Alzheimer’s.

3. Vascular Dementia: Sometimes called “Post Stroke Dementia”, Vascular Dementia is actually brain damage traced to cardiovascular problems or mini-strokes that cause bleeding or harm in the brain. It commonly happens following a stroke. Simply put, Vascular Dementia presents itself mostly through cognitive changes as a result of brain damage. The use of medications has been shown to prevent or slow further brain damage, therefore controlling the progress of Vascular Dementia.

4. Fronto-Temporal Dementia (FTD): This occurs when there is deterioration to the Frontal and Temporal Lobes of the brain. The person experiences problems with language and significant changes in their personality and behaviour. The Temporal lobe affects how one behaves or reacts in the world based on outward input while the Frontal lobe has to do with cognitive and emotional processes, and voluntary movement. When someone has FTD, they slowly withdraw into themselves or may lose inhibitions. They may also lose interest in others around them and their surroundings. Their emotions become empty and there is little to no awareness of the needs of others, and their verbal communication skills become predominantly weak and decrease significantly over time.

Causes

Genes play a role in dementia but patterns of inheritance vary. Current research shows that people who have a parent or sibling with Alzheimer’s are more likely to develop the disease than those who do not. Vascular dementia, dementia with Lewy bodies, and fronto-temporal dementia have not yet been linked to genetics in most cases. So out of the four common types of dementia, Alzheimer’s is the type with the most likely genetic link based on current research.

Environmental and lifestyle factors also greatly affect our chances of developing a particular disease we may have inherited. Fror this reason, it is important to develop an active, healthy lifestyle to avoid many types of illness.

Symptoms

Dementia requires a medical diagnosis but symptoms include; forgetfulness, memory impairment, falling, sleep disorder, paraphasia, limited social skills and thinking abilities so impaired that it interferes with daily functioning.

Having memory loss alone doesn’t mean that you have dementia. Memory loss has different causes but memory loss is one of the early signs of the condition.

Symptoms include cognitive decline, behavioural changes, changes in mood and other psychological conditions.

Cognitive: mental decline, struggle with visual and spatial abilities, disorientation, inability to speak or understand language, delusions, mental confusion, inability to recognise common things, difficulty handling complex tasks, or difficulty with planning and organising.

Behavioural: irritability, agitation, personality changes, restlessness, repeating questions, tasks and phrases; lack of restraint, or wandering and getting lost.

Mood: anxiety, loneliness, swings, or nervousness.

Psychological: depression, hallucination, anxiety, or paranoia

Muscular: inability to combine muscle movements or unsteady walking

The stages of dementia vary from person to person and the type of dementia. Keeping the four common types of dementia in mind, these seven stages are the usual progression that is experienced:

No symptoms yet, but tests might reveal a problem
Very mild changes in behaviour but independence remains
Mild decline is noticeable (e.g. changes in thinking, forgetting events, and repeating statements)
Moderate decline (trouble remembering recent events and handling money)
A moderate to severe decline where they forget names, are unsure what time of day it is, and need some assistance with basic daily tasks
Severe decline (forgetting their spouse’s name, their personality is changing, and they need help eating and going to the bathroom).
Very severe decline (unable to walk, can no longer speak their thoughts, and spend the most time in bed).

Treatment

Dementia can be helped but the condition cannot be cured. It is important to see a doctor if you or a loved one exhibits dementia symptoms. Some treatable medical conditions can cause dementia symptoms, so it’s important to determine the cause. Depending on the cause, some dementia symptoms might be reversible.

EVERYTHING YOU NEED TO KNOW ABOUT AMPHETAMINE STIMULANTS, INHALANTS AND SOLVENTS, COUGH SYRUPS

Background

In 2014, there were an estimated 246 million (range 162 -324 million) people in the world that have used an illegal drug in the past 12 months. The drugs used include cannabis, opiates (such as heroin), cocaine and amphetamine-type stimulants. Globally, the most common illegal drug used is cannabis. In Nigeria, drug use problems are found throughout the country but there are no official estimates of the number of drug users in the country. However, the numbers are considered large enough to be of concern.

The most common illegal drug used in Nigeria is cannabis. Other illegal drugs used include cocaine, heroin, amphetamine-type stimulants, inhalants and solvents such as glue. There are a lot of misunderstandings about the type of drugs people use and their side effects. This article outlines brief and accurate information on some major drugs used in Nigeria.

Note: We wrote about Cannabis in the first instalment of this series and about Cocaine and Heroin in the second.

 

 

Amphetamine-type Stimulants

Common names for amphetamine and methamphetamine in Nigeria: Players, Boys, Nuts, Speed, Uppers, Heart, Heat, Ice, Crystal, Fire and Glass.

Amphetamines are synthetic (chemical, not a natural product) stimulant drugs that speed up the messages travelling between the brain and the body. Amphetamines are generally swallowed but can also be injected, smoked or snorted. A type of amphetamine called methamphetamine commonly comes in small chunky clear crystals that look like frozen ice, while amphetamine commonly comes in a powder form.

Methamphetamine: Factsheet – Positive Choices

Methamphetamine is generally stronger, more addictive and causes more harm. When it is smoked or injected, the effect is usually in 3-7 seconds, but if swallowed, the effect takes place in 15-30 minutes. The duration of effect can last up to 6 hours.

Short-term effects:

Euphoria (intense excitement and happiness)
High levels of energy
Excitement
Increased heart rate
Anxiety and Paranoia
Increased confidence and talkativeness
Reduced appetite (less hungry)
Excessive sweating
Increased sex drive
Long-term effects:

Jaw clenching and teeth grinding
Feeling powerful or better than others
Becoming hostile or aggressive
Reduced appetite and extreme weight loss
Restless sleep
Dry mouth and dental problems
Regular colds and flu
Trouble concentrating
Difficulty breathing
Muscle stiffness
Anxiety, paranoia, psychosis
Depression
Heart and kidney problems
Increased risk of stroke
Needing to use more to get the same effect (developed tolerance)
Dependence on amphetamines
Withdrawal symptoms from amphetamine or methamphetamine generally fade after a week and mostly disappear after a month. Some withdrawal symptoms can include cravings for the drug, increased appetite, confusion and irritability, aches and pains, exhaustion, restless sleep and nightmares, and anxiety, depression and paranoia.

 

Inhalants and Solvents

Inhalant Abuse & Addiction | Types, Effects, & Treatment

Common names for Inhalants and Solvents in Nigeria: Shaba, Dogua, Solution, Helicopter and Sholisho

Inhalants and solvents are sometimes referred to as volatile substances and found in household, industrial and medical products – including glue, paint, petrol, aerosols, cleaning fluid, and gases – which produce vapours that some people (mostly adolescent and young people) breathe in (via nose or mouth) to get intoxicated or ‘high’. Inhaled fumes enter the bloodstream quickly and the effects are experienced in a few seconds often lasting 2-45 minutes. The effects can be similar to alcohol. Regular use can result in dependence.

Short-term effects:

Initial “high”
Giggling and laughing
Drowsiness and headaches
Bloodshot or glazed eyes
Blurred vision
Nose bleeds, runny nose, sneezing
Bad breath
Agitation and aggression
Long-term effects:

Irritability and depression
Memory loss
Reduced attention span and ability to think clearly
Pimples, rashes or blisters around the mouth and lips
Tremors (body shaking), weight loss and tiredness
Loss of sense of smell and hearing
A majority of long-term effects can be reversed if the person stops using solvents but some cleaning and other products can leave permanent damage to the brain.

Withdrawal symptoms usually start 24-48 hours after the last use and can last for 2 to 5 days. Common withdrawal symptoms can include headache, nausea and stomach pain, anxiety and depression, tiredness and tremors, body cramps and hallucinations (seeing and sensing something that does not exist).

 

Cough syrups

How cough syrup in Nigeria is creating a generation of addicts – BBC News

Common names for cough syrup in Nigeria (e.g. Coldex, Exol) in Nigeria: Koko, Coco, Crude oil, Slow, Yaro Matunwa, Benylin with Codeine.

Some cold and cough medicines are mind-altering at higher-than-recommended dosages. Cough medicines are easy to purchase, relatively cheap, and often do not require a doctor’s prescription and misuse is reported in Nigeria. A common ingredient found in many cough and cold medications is either Dextromethorphan (DXM) or Promethazine-codeine. Cough and cold medicines are mostly in tablet, capsule or syrup form. Some people mix cough syrup with flavoured drinks, alcohol or cannabis.

Short- and long-term effects

Euphoria, calming, numbness, nausea or vomiting, increased heart rate and blood pressure, slurred speech, dizziness and blurry vision. In higher doses, there can be sensations of physical distortions and hallucinations. Promethazine-codeine cough syrup can lead to a higher risk of fatal overdose (slowing or stopping the heart and lungs) and this risk increases when mixed with alcohol. Long-time use can lead to physical and psychological dependency.

Withdrawal Symptoms

Sleep disturbances, nausea, fast pulse, raised blood pressure, sweating, weakness and headaches. To address dependency, detoxification and rehabilitation will be required.

 

(This was originally published as a response to drugs and related organised crime in Nigeria, developed in collaboration with UNODC and Nigerian stakeholders and funded by the European Union).